Abnormal enhancement is not seen in PMD as opposed to some demyelinating disorders such as adrenal leukodystrophy in which enhancement is seen at the periphery of the active demyelination.

PMD中不会有异常的强化，相反其他的脱髓鞘病变如肾上腺脑白质营养不良症其外周活动性的脱髓鞘病变可以强化。