In the past, large families were necessary to find genes, but in this study only samples from one Quebec and one American patient were used to accomplish this.

对过去来说，需要进行大量家系筛选才能找到相应的基因，但此项研究中，仅使用一例来自加拿大魁北克和一例来自美国的样本就完成了此项研究。