Genetic etiology play a part of role in ASD, and genes mutated causing autism and epileptic encephalopathy and mental retardation have an overlap.

在自闭症群体中，遗传因素导致的占相当一部分。基因突变引发的孤独症、合并癫痫和智力发育迟缓有很多相同的共病基因。