It has been proved that ERS can interfere the differentiation of chondrocyte, decrease the synthesis of abnormal protein, attenuate the injury of cell.

有研究证实内质网应激能影响软骨细胞的分化，同时也抑制了软骨细胞的合成功能，减少异常蛋白的合成，减轻应激对细胞的损害。