One possibility relates to the ATP-making machinery's emission of free radicals, which are thought to contribute to aging and to such age-related diseases as cancer by damaging cells.
Although copper and stone tools continued to be used, bronze was far more successful in creating sharp edges that could be used as anything from saws and scythes to weapons.
Yet traditional measures of manufacturing productivity have shown significant increases despite the under measurement of quality, whereas service productivity has continued to stagnate.
If you can carry out the word "make" with a firm hand, and have a series of academic knowledge and action as well as operation, even if the old will turn into the new and weighty things.